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Check with this quick test to see if this new treatment​ may be right for you

*This short questionnaire is not intended for the purpose of providing medical advice but to see if you qualify to participate in the clinical trial. 


Clinical Trial 

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A new Skin Cancer treatment alternative to surgery

 for Squamous Cell Carcinoma.

A new treatment approach using powerful alpha particles is now available in a clinical trial which offers a minimally-invasive alternative to surgery, excision, or external radiation. The treatment is performed under local anaesthesia in an out-patient setting and without incision or stitches.

This innovative treatment, available in a FDA-approved clinical trial enrolling at leading cancer centers across the US may be right for you.

About Alpha DaRT
How does it work

How does the treatment works ?

The treatment involves the minimally invasive insertion of thin wires called “temporary implants” which emit radiotherapeutic alpha particles directly into the lesion. The temporary implants are then removed from the lesion a few weeks after insertion. Both the insertion and removal procedures are performed on an outpatient basis under local anesthesia.

Alpha particles are extremely powerful at destroying cancerous cells, but because they can only travel short distances, their impact on healthy surrounding cells is minimal. The Alpha DaRT™ is an innovative technology which was designed to deliver these alpha particles with localized precision to destroy the lesion while sparing surrounding healthy tissue, thereby minimizing side effects.

The treatment demonstrated* a 100% Complete Response (entire tumor removal), as well as the following advantages :


No costs for patients

No incision, stiches

Compatible with daily routine

No reconstructive surgery

One time treatment

Local anethesia

* After 12 weeks with no treatment-related adverse events reported to date, from a recent study, published in JAMA Open.


Patient stories

Below are some testimonials from people who chose Alpha DaRT for treating their skin cancer. Hear their insights as they share their personal stories and experiences with the Alpha DaRT.

Patients Stories

By the time Cyril had learned about the Alpha DaRT, his squamous cell carcinoma kept coming back despite multiple previous treatments. He feared that additional surgery would leave him blind because the lesion was close to his eye. Hear how Cyril was happy to find out about a new treatment option called Alpha DaRT that could save him from a major surgery near the eye and prevent sight loss.

Cyril: Was afraid of vision loss.

What to expect when joining the trial



The information you provide will be used strictly for study purposes. Please visit our privacy policy to learn more.

The initial eligibility process, including this questionnaire, should take only a few minutes to complete.

1.  Fill out the questionnaire

Therapy Session

2. Confirm initial trial eligibility with a study specialist


One of our study specialists will reach out to you to make sure that you fully understand and feel comfortable with the trial. They will ask you general health questions as necessary to determine if you may be eligible, and will do their best to address any questions or concerns you may have. If eligible, you will then be referred to a clinical trial site.

3. Meet with physician and clinical team at clinical trial site


The physician and clinical team will offer you a free consultation, explain the clinical trial in detail, and answer any questions you may have. They will then schedule your treatment along with any follow-up visits that may be required.

To find a participating medical center around you

Doctor and Patient

4. Treatment phase


The treatment is an outpatient procedure done under local anesthesia. During the treatment, thin wires called “sources” will be inserted into the lesion. The lesion will be bandaged and the sources will be left in place for approximately two weeks, following which you will be asked to return to the clinic to remove the sources. During this two-week period, you can continue with your daily routine as usual. After the treatment, the clinical team will continue to monitor your progress and you will attend some follow-up visits for further clinical evaluation by your physician.

Participate in Clinical Trial

 ? Is Alpha DaRT right for you

If you have :

✓   SCC (Squamous Cell Carcinoma)

✓   Recurrent (previously treated)

✓   Non metastatic (has not spread)

✓   And if you are looking for an alternative to surgery

In any of these :

✓   Cheek (external)

✓   Ear

✓   Nose 

✓   Forehead

✓   Skull

✓   Limbs (hands, feet)


✓   Scalp


Check with a few questions to see if you may be eligible

  • How do I participate in this trial?
    First, fill out the questionnaire, which should take no more than 5 minutes. At the end of the questionnaire you will receive a message saying whether you may or may not be eligible to participate. If the questionnaire indicates that you may be eligible, then one of our specialists will promptly reach out to you to provide support and information for the next steps.
  • What are the side effects?
    Results from clinical trials show that the treatment has been well tolerated with minimal side effects. Not all patients have side effects but some do, the most common side effects include local pain, redness at the implantation site frequently followed by minor swelling, and mild skin ulceration and which are typically resolved within 3-5 weeks. The majority of patients can resume normal activity shortly after treatment. Discuss your specific case with your physician to fully understand the potential risks associated with the treatment.
  • What are the costs of participating in the trial?
    There is no cost to participate in this clinical trial and you may also be eligible for reimbursement of reasonable travel-related costs. Check with the study staff team and your study's specialist.
  • Whom can I contact to learn more?
    Please feel free to contact us by email at or by phone 617 830 2870. We will do our best to respond promptly to all inquiries.
  • What is the difference between this treatment and Mohs surgery?
    FILL IN Mohs surgery is the gold standard for Squamous cell carcinoma, though in some cases it can be aggressive and leave scars and result in deformation and the need for reconstruction. Alpha DaRT treatment is a temporary implant that inserted into the lesion under local anesthesia and in outpatient setting. The procedure does not include incision or stitches.
  • What is the difference between this treatment and conventional radiotherapy?
    The most common Radiotherapy is external beam radiotherapy which high energy source that is external which effects the lesion but also harms healthy tissue. In order to minimize the effect on healthy tissue the treatment is usually given over a few weeks. Alpha DaRT is directly inserted into lesion and therefore has minimal effect on healthy tissue and therefore is administered in a single session.
Contact Us

For more information about your treatment options, speak with a Patient Specialist.



© Alpha Tau Medical Ltd.

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