Publications

Pre-Clinical Publications

2021

The Potentiation of Anti‐Tumor Immunity by Tumor Abolition with Alpha Particles, Protons, or Carbon Ion Radiation and Its Enforcement by Combination with
Immunoadjuvants or Inhibitors of Immune Suppressor Cells and Checkpoint Molecules

2020

Effective treatment of metastatic cancer by an innovative intratumoral
alpha particle-mediated radiotherapy in combination with
immunotherapy: A short review

2020

Diffusing alpha-emitters radiation therapy: approximate modeling of the
macroscopic alpha particle dose of a point source

2020

RIG-1-Like Receptor Activation Synergizes With Intratumoral Alpha Radiation to Induce Pancreatic Tumor Rejection, Triple-Negative Breast Metastases Clearance, and Antitumor Immune Memory in Mice

2019

Combining alpha radiation‑based brachytherapy with immunomodulators promotes complete tumor regression in mice via tumor‑specific long‑term immune response

2016

Inhibition of mouse breast adenocarcinoma growth by ablation with intratumoral alpha-irradiation combined with inhibitors of immunosuppression and CpG

2015

Tumor ablation by intratumoral Ra-224 loaded wires induces anti-tumor immunity against experimental metastatic tumors

2015

Ablation of experimental colon cancer by intratumoral 224 Radium-loaded wires is mediated by alpha particles released from atoms which spread in the tumor and can be augmented by chemotherapy

2014

Activation of local and systemic anti‑tumor immune responses by ablation of solid tumors with intratumoral electrochemical or alpha radiation treatments

2012

Intratumoral Ra-224-loaded wires spread alpha emitting atoms inside solid human tumors in athymic mice and can achieve local tumor control

2012

Enhanced killing of cervical cancer cells by combinations of methyl jasmonate with cisplatin, X or alpha radiation

2012

Comparative in vitro microdosimetric study of murine and human-derived cancer cells exposed to alpha particles

2012

Local control of experimental malignant pancreatic tumors by treatment with a combination of chemotherapy and intratumoral 224Radium-loaded wires releasing alpha-emitting atoms

2010

Treatment of solid tumors by alpha emitters released from 224Ra-loaded sources – internal dosimetry analysis

2009

Local control of lung derived tumors by diffusing alpha-emitting atoms released from intratumoral wires loaded with Radium-224

2009

Interstitial wires releasing diffusing alpha-emitters combined with chemotherapy improved local tumor control and survival in squamous cell carcinoma bearing mice

2008

Growth retardation and destruction of experimental squamous cell carcinoma by interstitial radioactive wires releasing diffusing alpha-emitting atoms

2007

Treatment of solid tumors by interstitial release of recoiling short-lived alpha emitters