טיפול מדויק וממוקד בסרטן
Publications
Clinical Publications
2020
Initial Safety and Tumor Control Results from a “First-in-Human” Multicenter Prospective Trial Evaluating a Novel Alpha-Emitting Radionuclide for the Treatment of Locally Advanced Recurrent Squamous Cell Carcinomas of the Skin and Head and Neck
2019
Clinical evidence of abscopal effect in cutaneous squamous cell carcinoma treated with diffusing alpha emitters radiation therapy: a case report
Pre-Clinical Publications
2022
A New Approach for a Safe and Reproducible Seeds Positioning for Diffusing Alpha-Emitters Radiation Therapy of Squamous Cell Skin Cancer: A Feasibility Study
2021
The Potentiation of Anti‐Tumor Immunity by Tumor Abolition with Alpha Particles, Protons, or Carbon Ion Radiation and Its Enforcement by Combination with
Immunoadjuvants or Inhibitors of Immune Suppressor Cells and Checkpoint Molecules
2020
Effective treatment of metastatic cancer by an innovative intratumoral
alpha particle-mediated radiotherapy in combination with
immunotherapy: A short review
2020
Diffusing alpha-emitters radiation therapy: approximate modeling of the
macroscopic alpha particle dose of a point source
2020
RIG-1-Like Receptor Activation Synergizes With Intratumoral Alpha Radiation to Induce Pancreatic Tumor Rejection, Triple-Negative Breast Metastases Clearance, and Antitumor Immune Memory in Mice
2019
Combining alpha radiation‑based brachytherapy with immunomodulators promotes complete tumor regression in mice via tumor‑specific long‑term immune response
2016
Inhibition of mouse breast adenocarcinoma growth by ablation with intratumoral alpha-irradiation combined with inhibitors of immunosuppression and CpG
2015
Tumor ablation by intratumoral Ra-224 loaded wires induces anti-tumor immunity against experimental metastatic tumors
2015
Ablation of experimental colon cancer by intratumoral 224 Radium-loaded wires is mediated by alpha particles released from atoms which spread in the tumor and can be augmented by chemotherapy
2014
Activation of local and systemic anti‑tumor immune responses by ablation of solid tumors with intratumoral electrochemical or alpha radiation treatments
2012
Intratumoral Ra-224-loaded wires spread alpha emitting atoms inside solid human tumors in athymic mice and can achieve local tumor control
2012
Enhanced killing of cervical cancer cells by combinations of methyl jasmonate with cisplatin, X or alpha radiation
2012
Comparative in vitro microdosimetric study of murine and human-derived cancer cells exposed to alpha particles
2012
Local control of experimental malignant pancreatic tumors by treatment with a combination of chemotherapy and intratumoral 224Radium-loaded wires releasing alpha-emitting atoms
2010
Treatment of solid tumors by alpha emitters released from 224Ra-loaded sources – internal dosimetry analysis
2009
Local control of lung derived tumors by diffusing alpha-emitting atoms released from intratumoral wires loaded with Radium-224
2009
Interstitial wires releasing diffusing alpha-emitters combined with chemotherapy improved local tumor control and survival in squamous cell carcinoma bearing mice
2008
Growth retardation and destruction of experimental squamous cell carcinoma by interstitial radioactive wires releasing diffusing alpha-emitting atoms